Friday, February 27, 2009

Scientists Discover Why Teeth Form in a Single Row - MarketWatch


A system of opposing genetic forces determines why mammals develop a single row of teeth, while sharks sport several, according to a study published today in the journal Science.

Scientists Discover Why Teeth Form in a Single Row - MarketWatch


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Friday, November 14, 2008

A New Method to Alter Genetic Code

PIGS really could save our bacon. Organs that are invisible to our immune system and so won't be rejected when they are transplanted could be ready within 10 years, thanks to a faster way of genetically engineering pigs.

Progress towards these "xenotransplants" has stalled through lack of funding and problems with the cloning technique used to engineer the pigs. Now there is a simpler way. The new technique will alter the DNA in a boar's sperm cells, and therefore in any future offspring, by injecting a virus into its testicles carrying the desired genes - such as those used to "disguise" pig organs. When the boars breed naturally, they should pass on the genetic changes to 

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Thursday, September 18, 2008

Simulation Based Research by Henry Markham

Henry Markham proposes 'simulation based research'  

  1. Reverse Engineer natural processes.

  2. Generate Neurons

  3. Reverse Engineer Electrical Types.

  4. Molecular Basis of Electrical Diversity

  5. Forward Engineering Single Neuron Models

  6. Probe Neuron Models

  7. The channelome project

The human “channelome,”  comprises families of
membrane ion channel proteins regulating bodily functions—some
400 genes, mixed and matched.

  1. Placing snapses

    1. Blue Builder Simulation Package

  2. Capturing snaptic transmission

    1. 6 types of snapsis

    2. anatomy of Martinotti Loops

  3. Network Activity

    1. Most processing is analog

Blue Brain has no hypothesis so it had funding problems in the US.

Emergent properties

  1.     Consciousness?

IT challenge

  1. workflows

  2. supercomputers

  3. build neurons



    2. Analysis

Blue Brain is a facility to build circuits 

  1.         The future is virtual labs

Funding is trivial

  1.     over 1000 different diseases affected by the brain circuits

Robotic Surgery on the Rise

Robotic surgical device manufacturing is at the burgeoning intersection of the automation industry and the medical instrumentation field. Although the current-day technology has existed since the early 2000s, the last couple of years have seen a large upswing in robotic surgery procedures.

The market for robot-assisted medical systems grew from $626.5 million in 2007 to an estimated $1 billion in 2008, according to a report published by Research and Markets. At the current rate, it is forecast to expand to $14 billion by 2014.

Much of this growth has been driven by sales of the "da Vinci" robotic system, developed by Intuitive Surgical. According to Barron's, the number of patients who underwent da Vinci surgery last year soared to 85,000, an increase of 75 percent from 2006. System sales rose by 42 percent over the same period.
The system's tiny robot arms are able to go places where human hands cannot, such as between the ribs in order to access the heart. The arms follow commands given by a surgeon in another room, who monitors the operation on a magnified screen. This process is particularly helpful for high-risk patients who would normally be considered poor candidates for intensive surgery.

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Tuesday, June 03, 2008

The Hidden Talents of the Lowly Sea Cucumber | Popular Science


A recent study shows that a gene in the sea cucumber blocks transmission of the parasite that causes malaria. Passed to humans by mosquitoes, malaria threatens around 40 percent of the world's population and is blamed for up to a million deaths a year. The idea is to incorporate the gene into mosquitoes, causing them to produce the protein lectin, which is poisonous to the malaria parasite early in development. The new, genetically modified mosquitoes would be released into the wild in hopes that they reproduce and spread the new gene to future generations and tamp out the spread of malaria.

The Hidden Talents of the Lowly Sea Cucumber | Popular Science


Cancer Risk Linked To Gum Disease

This looks like another indicator of inflammation risk.


The researchers found that after adjusting for details about the history of smoking, dietary factors, and other known risk factors, participants with a history of gum disease were 14% more likely to develop any type of cancer compared to those without history of gum disease.

Cancer Risk Linked To Gum Disease

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Wednesday, March 12, 2008

Printable Robots - OhmyNews International


Consider recent advances in inkjet printing. The same basic technology in a $100 home printer has been used by researchers at the Wake Forest University School of Medicine in North Carolina for the printing of "bio-ink" skin tissue as potential grafts for burn victims. It may also provide the basis for the printing of complete artificial organs such as kidneys and livers.

Printable Robots - OhmyNews International

Monday, February 11, 2008

The Race to Read Genomes on a Shoestring, Relatively Speaking - New York Times


A person wanting to know his or her complete genetic blueprint can already have it done — for $350,000.

But whether a personal genome readout becomes affordable to the rest of us could depend on efforts like the one taking place secretly in a nondescript Silicon Valley industrial park. There, Pacific Biosciences has been developing a DNA sequencing machine that within a few years might be able to unravel an individual’s entire genome in minutes, for less than $1,000. The company plans to make its first public presentation about the technology on Saturday.

The Race to Read Genomes on a Shoestring, Relatively Speaking - New York Times

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