Henry Markham proposes 'simulation based research'
- Reverse Engineer natural processes.
- Generate Neurons
- Reverse Engineer Electrical Types.
- Molecular Basis of Electrical Diversity
- Forward Engineering Single Neuron Models
- Probe Neuron Models
- The channelome project
The human “channelome,” comprises families of
membrane ion channel proteins regulating bodily functions—some
400 genes, mixed and matched.
- Placing snapses
- Blue Builder Simulation Package
- Capturing snaptic transmission
- 6 types of snapsis
- anatomy of Martinotti Loops
- Network Activity
- Most processing is analog
Blue Brain has no hypothesis so it had funding problems in the US.
- Consciousness?
IT challenge
- workflows
- supercomputers
- build neurons
- VISUALIZATION
- INTERACTIVE VISUALIZATION
- Analysis
Blue Brain is a facility to build circuits
- The future is virtual labs
Funding is trivial
- over 1000 different diseases affected by the brain circuits